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Image Search Results
Journal: Scientific Data
Article Title: A genomic data archive from the Network for Pancreatic Organ donors with Diabetes
doi: 10.1038/s41597-023-02244-6
Figure Lengend Snippet: Complementary methods for detecting genetic variants associated with T1D. ( a ) The effect size of any given variant on T1D risk is inversely related to the frequency of the variant . ( b ) To detect more commonly observed variants, DNA samples from nPOD donors were probed for the presence of SNPs previously reported in T1D GWAS efforts using the UFDIchip, yielding CEL microarray image files (modified from Affymetrix Axiom website: https://www.affymetrix.com/products_services/arrays/specific/axiom_mydesign.affx ). ( c ) To detect rare or novel variants, whole exome sequencing (WES) was performed on DNA from nPOD donors (modified from Roche NimbleGen SeqCap EZ Exome Library workflow ). Diagrams created in BioRender.
Article Snippet: Fig. 1 Complementary methods for detecting genetic variants associated with T1D. ( a ) The effect size of any given variant on T1D risk is inversely related to the frequency of the variant . ( b ) To detect more commonly observed variants, DNA samples from nPOD donors were probed for the presence of SNPs previously reported in T1D GWAS efforts using the UFDIchip, yielding
Techniques: Variant Assay, Microarray, Modification, Sequencing